Endocrine Abstracts

Introduction: Congenital adrenal hyperplasia encompasses a spectrum of autosomal recessive disorders marked by enzymatic deficiencies in cortisol biosynthesis. The prevailing etiology predominantly involves a deficit in 21-hydroxylase. This pathophysiological state gives rise to a myriad of complications, with acute adrenal insufficiency standing out as the most critical. Nevertheless, it is noteworthy that less-explored are the intricacies of additional complications, particu...

Introduction: During the COVID-19 pandemic, an increase of new-onset diabetes has been reported in various diabetes centers with many studies speculating an auto-immune-triggering mechanism while other studies hypothesizing an increase of type 2 diabetes (T2D).Aim: The aim of this study is to compare the type of new-onset diabetes presenting with a diabetic ketoacidosis and its prevalence in the pre-pandemic vs pandemic COVID-19.Me...

Introduction: COVID-19 has been incriminated directly and indirectly in the increase of patients presenting with diabetic ketoacidosis.Aim: The aim of this study is to compare diabetic ketoacidosis precipitating factors in the pre-pandemic and during the pandemic.Methods: This is a retrospective comparative study between patients hospitalized in the diabetology department in the university hospital Farhat Hached of Sousse for diabe...

IntroductionSomatotropic adenomas in the elderly are rare, and characterized by diagnostic delay and non-specific clinical signs. We report three cases of acromegaly discovered at a late age.ObservationThey are three women aged 66, 68 and 77 respectively. The circumstance of discovery of acromegaly was goiter in the first case (P1), poorly controlled diabetes in the second case (P2) and dysmorphic syndrome in...